Focal Segmental Glomerulosclerosis

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Definition: 

Focal Segmental glomerulosclerosis (FSGS) is a type of glomerular disease. FSGS causes scarring (sclerosis) in your kidney.  The scarring of FSGS only takes place in small sections of each glomerulus (filter), and only a limited number of glomeruli are damaged at first. The types of FSGS include: Primary, Secondary, and Genetic/ Familial FSGS.  

Both children and adults can be affected by FSGS. Males are at a slightly greater risk than females. African American individuals are more likely to be affected by this disease. FSGS is a very serious condition and can often lead to kidney failure.  

Symptoms: 

  • Swelling in various body parts 
  • Protein in urine 
  • Low protein in blood  
  • High cholesterol  
  • High blood pressure  
  • Foam in urine 

Treatments: 

  • ACE inhibitors  
  • Diuretics 
  • Plasmapheresis 
  • Immunosuppressive medications 
  • Low protein diet 
  • Corticosteroids  

 





 

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